Figure 2

Distribution of the 1608 putative MrpC binding sites relative to the nearest predicted TSC. (A) Distances from the ChIP-seq peaks to predicted TSCs. The genomic coordinate of each peak and that of its closest partner in the replicate dataset were averaged, and the distance between this average coordinate and the nearest predicted TSC was then calculated. The resulting distances are plotted as a frequency histogram. (B) Distances from randomized peaks to predicted TSCs. Monte Carlo simulation was used to generate a matching number of randomized locations within the genome for comparison with the ChIP-seq dataset. The distance between each randomized location and the nearest predicted TSC was then calculated, and the resulting distances are plotted as a frequency histogram.