Table 2 Gene ontology enrichment analysis on the transcriptomes of FW vs SW 1 h in medaka intestine (p < 0.05)

1

protein phosphorylation

1.90E-10

protein binding

8.60E-13

integrin complex

1.60E-03

2

regulation of transcription, DNA-dependent

1.10E-08

protein tyrosine kinase activity

8.10E-08

extra cellular region

7.50E-03

3

cell adhesion

4.20E-05

protein serine/threonine kinase activity

1.70E-05

Cytoskeleton

8.60E-03

4

regulation of small GTPase mediated signal transduction

2.20E-04

actin binding

4.20E-05

proteinaceous extracellur matri

2.30E-02

5

signal transduction

2.20E-04

sequence-specific DNA binding transcripttion factor activity

5.30E-05

6

integrin-mediated signaling pathway

1.01E-03

guanyl-nucleotide exchange factor activity

5.70E-04

7

intracellular signal transduction

1.72E-03

phospholipid binding

1.35E-03

8

glucose metabolic process

1.94E-03

sequence-specific DNA binding

2.12E-03

9

cytokine-mediated signaling pathway

2.27E-03

non-membrane spanning protein tyrosine kinase activity

2.69E-03

10

peptidy I-tyrosine dephosphorylation

2.43E-03

cytokine receptor activity

2.69E-03

11

cell cycle arrest

4.30E-03

ATP binding

3.86E-03

12

multicellular organismal development

5.18E-03

G-protein coupled peptide receptor activity

3.90E-03

13

G-protein coupled receptor signaling pathway

5.90E-03

protein domain specific binding

4.53E-03

14

neurotransmitter transport

9.35E-03

MAP kinase activity

5.07E-03

15

intracellular protein kinase cascade

1.75E-02

protien tyrosine/serine/threonine phosphatase activity

5.98E-03

16

MAPK cascade

1.79E-02

receptor activity

6.97E-03

17

transmembrane receptor protein tyrosine kinase signaling pat…

1.93E-02

calcium ion binding

7.11E-03

18

positive regulation of GTPase activity

2.71E-02

protein tyrosine phosphatase activity

1.02E-02

19

regulation of cellular component biogenesis

2.71E-02

transmembrane receptor protein tyrosine kinase activity

1.62E-02

20

hormophilic cell adhesion

3.446E-02

GTPase activator activity

1.76E-02

21

regulation of ARF protein signal transduction

3.48E-10

neurotransmitter: sodium symporter activity

2.08E-02

22

regulation of cellular component organization

3.48E-02

small GTPase regulator activity

2.20E-02

23

cell-matrix adhesion

4.77E-02

calmodulin binding

2.65E-03

24

polyol metabolic process

4.88E-02

organic acid transmembrane transporter activity

2.89E-02

25

ubiquitin protein ligase activity

2.99E-02

26

protein complex binding

3.27E-02

27

phosphotransferase activity, alcohol group as acceptor

3.67E-02

28

ARF guanyl-nucleotide exchange factor activity

3.92E-02

29

signal transducer activity

4.66E-02

30

kinase activity

4.79E-02