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Table 4 Biological processes enriched (p < 0.001) in the gene clusters significantly up-regulated (fold change > 1.5 and p-value < 0.01) after 30 min, 1 h and 4 h of DTT treatment, in comparison with the time immediately before addition of DTT

From: Investigation of protein secretion and secretion stress in Ashbya gossypii

30 min 1 h 4 h
Spermine biosynthetic process Protein unfolding DNA dealkylation involved in DNA repair
Interspecies interaction between organisms Bipolar cellular bud site selection  
  Early endosome to golgi transport Carbon utilization
S-adenosylmethionine transport Membrane docking Asexual reproduction
Traversing start control point of mitotic cell cycle Trehalose biosynthetic process Response to stimulus
  Phosphorus metabolic process Negative regulation of transferase activity
Macromolecule metabolic process Regulation of DNA repair  
Glucose 1-phosphate metabolic process Fructose transport Early endosome to golgi transport
  Asymmetric protein localization Cellular aldehyde metabolic process
Cis assembly of pre-catalytic spliceosome Vesicle-mediated transport NAD biosynthesis via nicotinamide riboside salvage pathway
  mRNA polyadenylation  
Macromolecule catabolic process Cellular localization Trehalose biosynthetic process
Protein unfolding Cell wall macromolecule catabolic process Protein unfolding
Golgi localization   Nuclear mRNA 5′-splice site recognition
Leading strand elongation Secretion  
Cellular macromolecule metabolic process Macromolecule localization Asymmetric protein localization
  Cofactor transport Secretion
Negative regulation of transcription from RNA polymerase II promoter during mitosis Oligosaccharide metabolic process Sodium ion transport
  Macromolecule catabolic process Negative regulation of developmental process
  Positive regulation of lipid metabolic process  
Proteolysis   Oligosaccharide metabolic process
Transcription initiation, DNA-dependent Transcription from RNA polymerase II promoter Tetrapyrrole catabolic process
   Intron homing
Stress-activated protein kinase signaling cascade Negative regulation of catalytic activity Negative regulation of catalytic activity
Negative regulation of transferase activity Regulation of hydrolase activity Regulation of hydrolase activity
  Regulation of transferase activity Regulation of transferase activity
Trehalose biosynthetic process Proteolysis Glycerophospholipid catabolic process
  Regulation of response to stimulus  
  Negative regulation of developmental process  
  1. GO terms highlighted in bold were overrepresented at two or all (bold italic) DTT exposure times.