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Figure 3 | BMC Genomics

Figure 3

From: Evolutionarily emerged G tracts between the polypyrimidine tract and 3′ AG are splicing silencers enriched in genes involved in cancer

Figure 3

The REPA G tracts-associated types of alternative splicing and examples of exons (genes) with the major types. A. Pie-shaped distribution of the relative abundance of different types of alternative splicing associated with the 627 REPA G tracts. The transcriptome-wide data was based on that by Wang et al., Nature’08. The biggest increase in the G tract group is the retained intron over that in the human transcriptomes. B. Examples of the major types of alternative splicing associated with the 3′SS G tracts. The exon numbers or gene names are indicated above or to the right of the splicing diagrams. Horizontal bar: G tract locations. Black boxes: alternative exons/introns. Narrower boxes: untranslated regions of mRNA. The intron/exon boundaries of alternative 3′ splice sites are indicated by arrowheads. The G tracts or G/A-rich motifs are underlined in the sequences. Black dots: potential branch points within the consensus “curay”.

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