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Table 4 BC-ratios of the neurodegenerative diseases and neurobalstoma computed under assumption, that only OMIM-derived seed genes have been mutated

From: Systems genomics evaluation of the SH-SY5Y neuroblastoma cell line as a model for Parkinson’s disease

Disease name Nodes Mutated (OMIM genes) Intact BC-ratio pBC-value
Huntington’s disease 63 2 61 0.536 <0.001
Alzheimer’s disease 248 13 235 0.495 < 0.001
Neuroblastoma 63 3 60 0.480 0.002
Amyotrophic lateral sclerosis 178 17 161 0.409 < 0.001
Parkinsons’s disease 358 15 343 0.379 < 0.001