Skip to main content

Table 4 BC-ratios of the neurodegenerative diseases and neurobalstoma computed under assumption, that only OMIM-derived seed genes have been mutated

From: Systems genomics evaluation of the SH-SY5Y neuroblastoma cell line as a model for Parkinson’s disease

Disease name

Nodes

Mutated (OMIM genes)

Intact

BC-ratio

pBC-value

Huntington’s disease

63

2

61

0.536

<0.001

Alzheimer’s disease

248

13

235

0.495

< 0.001

Neuroblastoma

63

3

60

0.480

0.002

Amyotrophic lateral sclerosis

178

17

161

0.409

< 0.001

Parkinsons’s disease

358

15

343

0.379

< 0.001