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Figure 3 | BMC Genomics

Figure 3

From: Cytokine systems approach demonstrates differences in innate and pro-inflammatory host responses between genetically distinct MERS-CoV isolates

Figure 3

Differentially expressed genes following MERS-CoV SA 1 and MERS-CoV Eng 1 infections. A. Statistically significant DE genes between MERS-CoV SA 1 and MERS-CoV Eng 1 were identified at 3, 7, 12, 18 and 24 hpi (absolute log2 FC > 1, FDR-corrected p-value < 0.05). The bargraph shows the number of up-regulated and down-regulated DE genes between MERS-CoV SA 1 and MERS-CoV Eng 1 at each time point. B. Heatmap of differentially expressed genes following MERS-CoV SA 1 and MERS-CoV Eng 1 infection shows more than four hundred genes uniquely expressed in MERS-CoV Eng 1 infected cells at early time points (between 3 and 12 hpi), with differential expression criteria of absolute log2 FC > 1 against time- and dataset-matched mocks, FDR-corrected p-value < 0.05).

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BMC Genomics

ISSN: 1471-2164

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