Parallel screens add power to find more shared hits. (A) We varied the number of used siRNAs and pathogens and calculated the rank of MET for L. monocytogenes in the ordered list of hit genes. We used PMM (and MTT for the case of one pathogen) over 1000 random resampling rounds with replacement. The color corresponds to the variation of the observed ranks. The boxplot shows that MET is a unique strong hit among the studied pathogens. The star indicates the boxplots that are significantly different from 0 (one sample t-test p < 0.05). (B) The figure shows the same experiment as in (A), but now with MTOR for Vaccianiavirus. The boxplot shows that MTOR is a shared significant hit for several pathogens. (C) The figure shows the same experiment as in (A) but with non-hit ALK for B. abortus for control.