Figure 7

Summary of differences of PMM top hits compared to other hit scoring methods. (A) Y-axis shows the PMM gene ranking for L. monocytogenes. X-axis is the same, but we randomized the other 7 parallel assays. The colors correspond to hit genes (FDR < 0.4) in different cases. Parallelism yielded only a slight effect on the ranking, but added genes to the list of significant hit genes. (B) The scatter plot shows PMM hit ranking (y-axis) compared to the MTT hit ranking (x-axis) for L. monocytogenes. The dot size corresponds to the sharedness score of each gene. Some genes with high sharedness scores gained statistical power.