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Table 3 Concordance of genome-wide association analyses for the California calves with the loci most strongly associated with BRDC susceptibility for all analyses

From: Susceptibility loci revealed for bovine respiratory disease complex in pre-weaned holstein calves

Chromosome (location Mb)

EMMAX-GRM+

GBLUP+

FvR+

EIGENSTRAT+

No. SNPs^

Lead SNP#

Score*

BTA15 (30–31)

1

1

1

30

18

rs41756356

33

BTA14 (63–64)

14

7

15

6

34

rs134331138

42

BTA3 (119–120)

65

9

7

5

11

rs41660991

86

BTA23 (3–4)

5

2

76

115

5

rs110158528

198

BTA15 (14–15)

156

67

19

3

1

rs136365736

245

BTA19 (9–10)

73

170

37

44

1

rs121919115

324

BTA6 (42–43)

79

21

171

65

12

rs43456007

336

BTA4 (47–48)

74

19

192

63

1

rs41651168

348

BTA14 (11–12)

147

64

3

178

2

rs133522438

392

BTA6 (40–41)

131

72

172

32

12

rs134070398

412

BTA13 (71–72)

45

187

34

155

7

rs110991341

421

BTA7 (10–11)

97

274

135

41

6

rs134195407

547

BTA18 (0–1)

35

313

198

72

32

rs109385868

618

BTA3 (46–47)

178

364

178

31

2

rs133069708

678

BTA2 (45–46)

143

29

287

227

1

rs136772856

686

BTA11 (71–72)

304

375

51

48

1

rs133739594

778

BTA12 (6–7)

76

84

418

210

1

rs135134119

789

BTA3 (107–108)

294

315

98

110

1

rs137396132

817

BTA12 (33–34)

306

176

355

34

1

rs133730139

871

BTA16 (36–37)

125

140

112

529

13

rs136788834

906

BTA6 (95–96)

191

35

82

652

2

rs41911495

960

  1. +Reflects the ranking of the best (lowest) ranked SNP for that genomic region for that analysis. Only scores <1000 are shown.
  2. ^Number of SNPs ranked among the top 200 SNPs (top 0.03%) that are found within this genomic region as being associated with BRDC susceptibility across the different analyses.
  3. #The rs SNP identification number for the SNP with the lowest ranking for the QTL.
  4. *Score is the sum of the ranks for the best ranked SNP for that genomic region across all analyses.