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Table 5 Concordance of genome-wide association analyses for the combined California and New Mexico calves with the loci most strongly associated with BRDC susceptibility for all analyses

From: Susceptibility loci revealed for bovine respiratory disease complex in pre-weaned holstein calves

Chromosome (location Mb)

EMMAX-GRM+

GBLUP+

FvR+

EIGENSTRAT+

No. SNPs^

Lead SNP#

Score*

BTA15 (30–31)

1

1

2

11

16

rs41756356

15

BTA19 (9–10)

40

188

20

1

1

rs121919115

249

BTA15 (31–32)

33

2

299

25

1

rs109057462

359

BTA11 (80–81)

123

103

71

64

9

rs133204524

361

BTA20 (0–1)

30

20

9

315

13

rs110484875

374

BTA3 (46–47)

55

192

91

81

2

rs133069708

419

BTA4 (47–48)

4

36

358

34

18

rs136678678

432

BTA17 (16–17)

26

3

49

397

3

rs135082107

477

BTA3(119–121)

41

339

118

82

3

rs110977672

580

BTA14 (11–12)

142

59

63

319

2

rs133522438

583

BTA17 (14–15)

80

135

26

391

20

rs110488418

632

BTA29 (48–49)

94

171

198

197

1

rs136036800

660

BTA4 (48–49)

21

209

455

3

7

rs110213301

688

BTA20 (0–1)

143

251

170

144

5

rs110513803

708

BTA16 (36–37)

162

280

224

92

14

rs136059947

758

BTA15 (14–15)

182

110

125

354

2

rs136365736

771

BTA3 (89–90)

342

146

138

147

2

rs136571247

773

BTA14 (81–82)

227

371

133

63

6

rs132956286

794

BTA18 (55–56)

107

26

647

26

1

rs136121374

806

BTA12 (58–59)

137

21

593

86

2

rs135900256

837

BTA7 (11–12)

297

207

4

378

1

rs134912653

886

BTA10 (1–2)

284

133

249

267

1

rs136001993

933

BTA17 (10–11)

105

480

100

260

2

rs136672854

945

BTA14 (62–63)

277

613

44

12

1

rs136594328

946

BTA20 (23–24)

60

202

461

254

9

rs109301681

977

  1. +Reflects the ranking of the best (lowest) ranking SNP for that genomic region for that analysis. Only scores <1000 are shown.
  2. ^Number of SNPs ranked in the top 200 SNPs (top 0.03%) that are found in this genomic region as associated with BRDC susceptibility across the different analyses.
  3. #The rs SNP identification number for the SNP with the lowest ranking for the QTL.
  4. *Score is the sum of the ranking of the best ranking SNP for that genomic region across all analyses.