Examples of differential expression of proteins implicated in signal transduction. Representative sections of 2DGE images (left panel) and representative Western blots (right panel) for sarcalumenin (SRL) (A), myozenin-1 (MYOZ1) (B), annexin A1 (ANXA1) (C), annexin A5 (ANXA5) (D) and glutathione S-transferase omega-1 (GSTO1) (E). In each panel, histograms represent normalized volume of protein spot (n = 5–6), and Western blot quantification (n = 7) for adult and old post-menopausal women. Results are indicated as means ± SE. *: P <0.05 indicates significant difference between adult and old women.