Examples of differential expression of proteins implicated in cytoprotection, cytodetoxification or proteolysis. Representative sections of 2DGE images (left panel) and representative Western blots (right panel) for aldehyde dehydrogenase (ALDH2) (A), α-crystallin B chain (HSPB5) (B), heat shock 70 kDa protein 1A/1B (HSPA1A) (C), HSP 90-beta (HSPC3) (D), and transitional endoplasmic reticulum ATPase (or valosin-containing protein, VCP) (E). In each panel, histograms represent normalized volume of protein spot (n = 5–6), and Western blot quantification (n = 7) for adult and old post-menopausal women. Results are indicated as means ± SE. *: P <0.05 indicates significant difference between adult and old women.