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Table 3 Transcription factor binding sites analyses at the promoters of the three genes

From: CAGE-defined promoter regions of the genes implicated in Rett Syndrome

TF p1@FOXG1 p2@FOXG1 p1@MECP2 p2@MECP2 p1@CDKL5 p2@CDKL5
RREB1 1.5 (p = 0.01)* 0.0 (p = 1.0) 0.0 (p = 1.0) 0.0 (p = 1.0) 0.7 (p = 0.08) 0.7 (p = 0.08)
FOXP1 1.3 (p = 0.03)* 0.7 (p = 0.1) 0.0 (p = 1.0) 0.0 (p = 1.0) 0.0 (p = 1.0) 0.0 (p = 1.0)
NFY 1.9 (p = 0.01)* 0.0 (p = 1.0) 1.3 (p = 0.02)* 1.9 (p = 0.01)* 0.9 (p = 0.09) 0.9 (p = 0.09)
TF pA@Foxg1 pB@Foxg1 p1@Mecp2 p2@Mecp2 p1@Cdkl5 p2@Cdkl5
RREB1 0.0 (p = 1.0) 0.9 (p = 0.06) 0.0 (p = 1.0) 0.34 (p = 0.6) 0.0 (p = 1.0) 0.0 (p = 1.0)
FOXP1 0.0 (p = 1.0) 0.0 (p = 1.0) 0.0 (p = 1.0) 0.2 (p = 0.7) 0.0 (p = 1.0) 0.0 (p = 1.0)
NFY 1.9 (p = 0.007)* 1.9 (p = 0.007)* 1.3 (p = 0.02)* 1.3 (p = 0.02)* 1.0 (p = 0.03)* 1.0 (p = 0.03)*
SP1 1.7 (p = 0.04)* 1.4 (p = 0.06) 2.5 (p = 0.01)* 2.5 (p = 0.01)* 2.6 (p = 0.01)* 2.6 (p = 0.01)*
  1. *Denotes significant values.
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