Figure 2
From: Identification of a novel Parkinson’s disease locus via stratified genome-wide association study
New region of association with Sporadic-PD. (A) Locations of PD-associated loci on the short arm of chromosome 1. (B) Enlargement of chromosomal region centered on the new signal and extending 1 Mb in each direction. Red bars are known genes. Hashed red bar, huseyo, is poorly annotated. Not all known/putative genes in the region are displayed. Blue bars are disease loci that have been mapped but the genes have not been characterized yet. (C) The LD structure of Sporadic-PD associated SNPs in the 2 Mb region. SNPs within 1 Mb on either side of top SNP, rs2338971, are plotted, showing –Log10 P values for their association with Sporadic-PD. (D) ENCODE data from UCSC Genome Browser showing evidence of regulatory sequences.