Table 4 Common, conserved Bacillus phage proteins of predicted function with at least 20 homologues
Pham # | Domain/Function | # Members | # Phages | Phages (cluster or phage name) |
|---|---|---|---|---|
DNA REPLICATION/METABOLISM | ||||
236 | DNA Polymerase I | 41 | 26 | I, J1, J2, J3, J4, J5, J6, J8, SP10, Bc431v3 |
274 | Chromosome Seg. ATPase | 38 | 25 | H2, J, BanS-Tsamsa |
247 | Class I RNR | 36 | 33 | H, I1, J, 0305φ836, BCD7, SP10, BanS-Tsamsa, SPB2 |
261 | Helicase | 28 | 28 | I, J, SP10 |
256 | SbcC-like Nuclease | 28 | 28 | I, J, SP10 |
257 | Endonuclease (SbcD) | 27 | 27 | I, J1, J2, J3, J4, J5, J6, J7, BPS10C, SP10, W.Ph., Hakuna, Megatron |
101 | Dihydrofolate Reductase | 27 | 27 | H2, J, BCD7, BanS-Tsamsa, G |
98 | Thymidylate Synthase | 24 | 24 | J, BCD7 |
99 | dNMP Kinase | 23 | 23 | J |
195 | Fumerate Reductase | 22 | 23 | J |
222 | Mre11 Nuclease | 23 | 23 | J |
232 | DNA Polymerase III | 23 | 23 | J |
238 | Histone | 23 | 23 | J |
252 | DUT | 23 | 23 | J |
258 | Replicative DNA Helicase | 23 | 23 | J |
229 | RecA-like | 23 | 23 | J |
254 | DNA primase | 23 | 23 | J |
246 | RNR beta subunit | 22 | 22 | H1, I1, J4, J5, J6, J8, 0305phi8-36 |
33 | Chromosome Seg. Protein | 22 | 22 | J1, J2, J4, J5, J6, J7, J8 |
244 | Glutaredoxin-like | 20 | 19 | J1, J2, J4, J5, J6, J8, SPBc2, BPS10c, BPS13, Megatron, W.Ph |
VIRION STRUCTURE AND ASSEMBLY | ||||
278 | Tail Assembly Chaperone | 46 | 23 | J |
89 | Phage Terminase Large | 34 | 28 | I, J, SP10 |
264 | Adsorption Tail | 29 | 27 | I, J1, J3, J4, J5, J6, J7, J8 |
291 | MCP | 29 | 28 | I, J, SP10 |
276 | Tail Lysin | 29 | 28 | I, J, SP10 |
295 | Portal protein | 28 | 28 | I, J, SP10 |
266 | Baseplate | 28 | 28 | I, J, SP10 |
283 | Structural Protein | 28 | 28 | I, J, SP10 |
284 | Tail Sheath | 28 | 28 | I, J, SP10 |
293 | Prohead Protease | 28 | 27 | I, J2, J3, J4, J5, J6, J7, J8, phiNIT1, SP10 |
265 | Baseplate J | 27 | 23 | J |
273 | Tail Lysin | 27 | 24 | J, BanS-Tsamsa |
277 | Major Capsid L1 Protein | 24 | 24 | J, SP10 |
88 | Terminase | 23 | 23 | J |
CELL LYSIS PROTEINS | ||||
276 | Cell Wall Hydrolase | 28 | 28 | I, J, SP10 |
282 | Murein Transglycosylase | 28 | 28 | I1, J, 0305φ8-36, SP10, BanS-Tsamsa |
226 | Holin | 23 | 23 | J |
198 | Holin | 23 | 23 | J |
267 | Lysozyme-like | 23 | 23 | J |
GENE REGULATION/HOST FUNCTIONS | ||||
35 | Bacterial SH3-like | 25 | 25 | C, E1, F, J5, J8, BanS-Tsamsa, PhiCM3 |
370 | FtsK DNA Translocase | 23 | 23 | C, E1, G, BV1, PM1, phIS3501, phBC6A51 |
260 | cAMP Regulatory Protein | 23 | 23 | J |
269 | MisL-like transporter | 23 | 23 | J |
292 | Membrane Protein | 23 | 23 | J |
155 | Metallo-beta-lactamase | 21 | 20 | J4, J5, J6, J7, J8, BanS-Tsamsa |