Meta-clustering identifies combinatorial subprofiles for chromatin marks. Meta-clustering identifies metaclusters of combinatorial subprofiles for different chromatin marks in K562. A) Heatmap of characteristic subprofiles in each metacluster. Each cell in the heatmap represents the correlation of a RTSS profile with one of five subprofiles identified from the clustering of each chromatin mark. B) Average subprofile over all RTSSs in each metacluster for each chromatin mark in K562. Plots for other cell-lines are in [Additional file 1: Figure S4 and S5].