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Figure 4 | BMC Genomics

Figure 4

From: Central role for RNase YbeY in Hfq-dependent and Hfq-independent small-RNA regulation in bacteria

Figure 4

Differential expression of sRNAs and their known targets in Δ ybeY and control (WT) bacteria. Complete linkage algorithm and a euclidean distance metric were used to cluster rows and columns simultaneously to generate heatmaps. Values were transformed to zero (row-wise) mean and unit (row-wise) variance prior to clustering. The sRNA clustering tree is shown on the left (A) and the previously target clustering tree is shown on the right (B). The color scale shown between A and B illustrates the relative expression level of the indicated sRNA and targets across all samples: red denotes expression >0 and green denotes an expression <0. sRNAs shown here are those detected on microarrays. (C) represents the pathways/functions of known targets of sRNAs (represented in (A) and (B).

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