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Table 1 Description of the datasets used in this study and the statistical evaluation of age-associated probes

From: Major aging-associated RNA expressions change at two distinct age-positions

Tissue Chronological datasets Permuted datasets (N=100)
Nr. samples Age range GT p-value * Age-regulated ** Age-regulated mean ± SE** [Ps>Cs/Ps<Cs]^
VL muscles 29 35-89 0.015 4101 2991 ± 86.1 7/93 [0.07]
Brain cortex 30 26-106 0.004 2339 677 ± 52.2 3/97 [0.03]
Kidney cortex 72 27-92 0.002 2397 1136 ± 77.2 11/89 [0.12]
Kidney medulla 61 29-92 0.205 1474 1090 ± 70.0 24/76 [0.31]
  1. Table shows the four datasets used in this study in chronological order and permuted samples. The number of samples and the age range (in years) are indicated.
  2. * The p-value determined with the globaltest (GT).
  3. ** The number of age-regulated probes (p-value < 0.05) was determined using a quadratic regression model and no age-association as null hypothesis. In the permuted datasets, the mean and the standard error (SE) from 100 permutations per dataset were calculated.
  4. ^The ratio between permuted samples (Ps) with a higher to lower number of significant probes, compared with chronologically ordered samples (Cs).