Figure 2

Hierarchical clustering heatmap showing similarities of t-statistics of the meQTLs across all cohorts. Each row represents one SNP-CpG site tested; only SNP-CpG combinations that were significant in at least one cohort are included here. Columns represent cohorts (labels at bottom), and the hierarchical clustering tree shows relative similarity in test statistics between the tissues and cohorts. Color represents strength and direction of association t-statistics (see color key). Cohort abbreviations from left to right: CB B: cord blood B, TCTX: temporal cortex, FCTX: frontal cortex, PONS: pons, CRBLM: cerebellum, CB A: cord blood A, and PB: peripheral blood.