Skip to main content

Table 1 List of mRNAs with increased polysome association during ER stress (treatment with DTT or TM)

From: Polysome profiling reveals broad translatome remodeling during endoplasmic reticulum (ER) stress in the pathogenic fungus Aspergillus fumigatus

DTT

TM

mRNA

Ribosomal proteins/translation

  

2.81

2.92

60S ribosomal protein L27a (AFUA_3G05600)

2.15

3.20

40S ribosomal protein S29 (AFUA_6G12720)

2.87

2.26

40S ribosomal protein S8 (AFUA_6G07360)#

2.80

2.16

50S ribosomal protein L36 (AFUA_4G12810)

2.59

2.32

37S ribosomal protein S16 (AFUA_5G08350)

1.48

2.60

Mitochondrial ribosomal protein L11 (AFUA_5G11830)

2.01

1.93

Ribosome biogenesis protein (AFUA_8G04790)

1.18

2.49

37S ribosomal protein S5 (AFUA_5G11540)

1.51

1.93

40S ribosomal protein S9 (AFUA_3G06970)#

1.01

2.42

40S ribosomal protein Rps16 (AFUA_2G10500)#

1.07

2.20

60S ribosomal protein L6 (AFUA_6G09060)

4.51

2.08

Aconitate hydratase/Mitochondrial ribosomal protein subunit L49 (AFUA_3G08080)#

3.11

1.36

Eukaryotic translation initiation factor 3 subunit eIF-Ca (AFUA_1G05200)

1.72

2.49

Translation elongation factor eEF-1B gamma subunit, putative (AFUA_1G17120)

1.27

2.52

GTP binding protein Guf1 (AFUA_3G14350)

1.86

1.05

Eukaryotic translation initiation factor 3 subunit eIF-Ck (AFUA_3G09280)

Cell membrane/cell wall

  

1.08

6.34

Squalene monooxygenase Erg1 (AFUA_5G07780)

1.61

1.43

Ergosterol biosynthesis protein Erg28 (AFUA_2G11550)

1.37

1.39

1,3-beta-glucanosyltransferase Gel2 (AFUA_6G11390)

3.51

4.88

Cell wall proline rich protein (AFUA_1G13450)

2.59

3.62

Actin cortical patch protein Sur7 (AFUA_2G02310)

4.21

2.23

CFEM domain protein (AFUA_6G14090)

1.36

1.89

GPI anchored protein (AFUA_2G07800)

1.78

1.01

GPI anchored dioxygenase (AFUA_3G01800)

1.24

3.13

Dolichol phosphate-mannose biosynthesis regulatory protein Dpm2 (AFUA_1G03020)

1.32

1.05

N-acetylglucosaminyl-phosphatidylinositol deacetylase, putative (AFUA_5G12550)

1.10

2.58

Integral membrane protein (Pth11) (AFUA_6G03600)#

Protein folding & modification

  

1.29

2.48

Alpha-1,2-mannosyltransferase (Alg2) (AFUA_5G13210)

1.83

2.58

Disulfide isomerase (TigA) (AFUA_5G12260)#

1.04

2.84

Protein disulfide isomerase Pdi1 (AFUA_2G06150)

1.04

1.82

N-acetyltransferase family protein (AFUA_4G10930)

1.35

1.47

N-acetyltransferase complex ARD1 subunit (AFUA_1G09600)

2.11

2.89

Prefoldin subunit 5 (AFUA_1G10740)#

Endosome/protein transport and sorting

  

1.71

1.94

Rho GTPase activator (Bem3) (AFUA_6G06400)

1.69

1.41

Fasciclin domain family protein (AFUA_1G14300)

3.75

1.50

Ras-like GTP-binding protein (AFUA_4G03100)

1.39

2.26

Endosomal cargo receptor (Erv14) (AFUA_6G07290)

1.58

2.16

Synaptobrevin-like protein Sybl1 (AFUA_6G11270)

1.57

3.04

RAB GTPase Vps21/Ypt51 (AFUA_3G10740)#

5.38

2.13

Vacuolar protein sorting 55 superfamily (AFUA_6G04780)#

1.03

2.77

AP-1 adaptor complex subunit sigma (AFUA_2G01570)

1.93

1.75

Mitochondrial import inner membrane translocase subunit (TIM22) (AFUA_5G02200)#

Transcription

  

3.07

3.04

bZIP transcription factor JlbA/IDI-4 (AFUA_5G01650)#

1.88

3.90

CBF/NF-Y family transcription factor (AFUA_2G14250)

4.34

1.41

C6 transcription factor (AFUA_3G09130)

2.03

3.35

Transcription factor RfeF (AFUA_4G10200)

1.03

4.24

CP2 transcription factor (AFUA_1G17350)

3.09

1.71

bZIP transcription factor (LziP) (AFUA_1G16460)#

1.84

2.39

Transcription initiation factor TFIID, 31kd subunit, putative (AFUA_1G14600)

2.18

1.29

C6 transcription factor (AFUA_6G11230)

1.48

1.08

RNA polymerase II mediator complex component Srb8, putative (AFUA_3G06250)

1.63

3.90

CHCH domain protein (AFUA_3G06370)#

2.44

1.48

Nitrogen metabolite repression regulator NmrA (AFUA_5G02920)

Stress response

  

1.24

1.99

General stress response phosphoprotein phosphatase Psr1/2 (AFUA_1G04790)#

4.37

3.43

Glutathione peroxidase Hyr1 (AFUA_3G12270)

  1. Values represent log2[translational efficiency ratio], as described in Methods. #Those mRNAs that were also subject to translational upregulation in the thermal stress dataset (37°C, 60 min).