Figure 2

Correlation between transcriptomic and proteomic datasets of genes differentially expressed in the C. difficile spo0A mutant compared to the parental C. difficile 630 Δerm strain. The degree of correlation are plotted as log2 fold change for all gene products that had been quantified in both proteome (y-axis) and RNASeq (x-axis) analyses. Significantly (p-adj < 0.01) disregulated proteins or transcripts are shown with red/brown (upregulated) and light green/dark green (downregulated) symbols. Protein groups that were positive in Significance B test of at least two biological replicates are depicted as significant (dark colours). See methods for analysis details. Note that no proteins were upregulated without being upregulated at the transcript level (“proteome up”).