Skip to main content
Figure 2 | BMC Genomics

Figure 2

From: Comparative genomics of enterohemorrhagic Escherichia coli O145:H28 demonstrates a common evolutionary lineage with Escherichia coli O157:H7

Figure 2

Comparative analysis of E. coli O145:H28 genomes. ACT alignment of the two E. coli O145:H28 chromosomes (A) and the two virulence plasmids, pO145-13514 and pO145-13516 (B) to demonstrate the conservation and the divergence between the genomes of the strains. Red color indicates the synteny between the two genomes, blue indicates the inversion, whereas white indicates no homologous sequences present between the two genomes. Regions 1, 2, and 3 on chromosome spanning the chromosome segments of 310,677-595,642, 1,789,072-1,980,931, and 5,269,949-5,398,918, respectively in strain RM13514. The first inversion in RM13514 is bordered by the mobile elements IE01 and P01, while the second inversion is bordered by P07 and P08, and the third inversion in RM13516 is bordered by IE06 and IE07. Regions A and B on pO145 represent a four gene cluster related to EHEC-hemolysin production and a four gene cluster related to lipid A modification, respectively.

Back to article page