Table 1 Genome characteristics of Escherichia coli O145:H28 and comparison with other genomes of STEC
| Â | E. coli O145:H28 | E. coli O157:H7 | E. coli O103 str. 12009 | E. coli O26 str. 11368 | E. coli O111 str. 11128 | E. coli O104 str. 2011C-3493 | |||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| Â | RM13514 | RM13516 | EDL933 | Sakai | EC4115 | TW14359 | Xuzhou21 | ||||
Chromosome | Â | Â | Â | Â | Â | Â | Â | Â | Â | Â | Â |
Size (bp) | 5,585,613 | 5,402,276 | 5,528,445 | 5,498,450 | 5,572,075 | 5,528,136 | 5,386,223 | 5,449,314 | 5,697,240 | 5,371,077 | 5,273,097 |
%GC | 50.7 | 50.7 | 50.4 | 50.5 | 50.5 | 50.5 | 50.5 | 50.7 | 50.7 | 50.6 | 50.7 |
CDSs | 5,613 | 5,324 | 5,298 | 5,230 | 5,315 | 5,255 | 5,039 | 5,054 | 5,364 | 4,972 | 4,975 |
tRNA | 104 | 98 | 98 | 105 | 110 | 106 | 93 | 98 | 101 | 107 | 94 |
rRNA | 22 | 22 | 22 | 22 | 22 | 22 | 22 | 22 | 22 | 22 | 22 |
Prophages (Prophage-like elements) | 15 (5) | 10 (2) | 9 (6) | 13 (5) | 10 (6) | 10 (6) | 8 (5) | 11 (4) | 13 (8) | 15 (2) | 6 (3) |
stx genes | stx2a | stx2a | stx1+2a | stx1+2a | stx2a +2c | stx2a+2c | stx1+2a | stx1 + 2a | stx1 | stx1 + 2a | stx2a |
Number of IS | 91 | 73 | 82 | 81 | 72 | 65 | 68 | 100 | 95 | 101 | 87 |
Number of IE | 7 | 7 | 5 | 6 | 5 | 5 | 5 | 6 | 9 | 7 | 5 |
LEE-island integration locus | selC | selC | selC | selC | selC | selC | selC | pheV | pheU | pheV | N/A |
pEHEC-like plasmid | Â | Â | Â | Â | Â | Â | Â | Â | Â | Â | Â |
Size (bp) | 87,120 | 98,066 | 92,077 | 92,721 | 94,644 | 94,601 | 92,728 | 75,546 | 85,167 | 77,690 | N/A |
GC (%) | 47.6 | 49.7 | 47.6 | 47.6 | 47.9 | 47.9 | 47.6 | 49.1 | 47.5 | 50.0 | N/A |
CDSs | 94 | 115 | 99 | 85 | 108 | 110 | 92 | 67 | 65 | 72 | N/A |
Number of IS | 27 | 16 | 10 | 11 | 12 | 10 | 12 | 13 | 26 | 16 | N/A |
Other plasmid(s) | Â | Â | Â | Â | Â | Â | Â | Â | Â | Â | Â |
Size (bp) | 64,561 | 58,666 | N/A | 3,306 | 37,452 | N/A | 37,785 | N/A | 63,365/5,686/4,073 | 204,604/97,897/8,140/6,673 | 88,544/74,217/1,549 |
%GC | 52.6 | 42.4 | N/A | 43.4 | 39.7 | N/A | 40.5 | N/A | 52.5/46.2/44.1 | 47.0/48.2/49.6/50.2 | 49.7/47.1/50.8 |
CDSs | 69 | 73 | N/A | 3 | 54 | N/A | 52 | N/A | 81/6/3 | 222/121/10/10 | 94/80/1 |
Number of IS | 6 | 0 | N/A | 0 | 0 | N/A | 0 | N/A | 1/0/0 | 14/2/0/0 | 18/3/0 |
Total genome size (bp) | 5,737,294 | 5,559,008 | 5,620,522 | 5,594,477 | 5,704,171 | 5,622,737 | 5,516,736 | 5,524,860 | 5,855,531 | 5,766,081 | 5,437,407 |
Total genome CDSs | 5,776 | 5,512 | 5,397 | 5,318 | 5,477 | 5,365 | 5,183 | 5,121 | 5,519 | 5,407 | 5,150 |