Mean breakpoint mismatch for various levels of (A) mean value of fragment lengths, (B) standard deviation of fragment lengths, and (C) read length. Here the base call error rate, depth of coverage, duplication size are fixed at 0.01, 40X and 10 Kbp, respectively. For (A) and (B), the read length is fixed at 75 bp. For (A) and (C), standard deviation of the fragment lengths is fixed at 10 bp. For (B), mean of the fragment lengths is 200 bp and for (C), this value is fixed at 400 bp.