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Table 2 Molecular evolution of ω and κ toxins from Australian funnel-web spiders

From: Diversification of a single ancestral gene into a successful toxin superfamily in highly venomous Australian funnel-web spiders

  FUBARa MEMEb PAMLc
  M8 M2a
ω ω >1d: 3 7 0 0
toxins ω <1e: 5 0 0
0.69 0.73
κ ω >1a: 1 0 0 0
toxins ω <1b: 0 0 0
1.06NS 1.06NS
ALL ω >1a: 3 8 1 0
toxins ω <1b: 7 (0 + 1) 0
0.78 0.83
  1. aFast, Unconstrained BayesianApproximation (FUBAR).
  2. bSites detected as experiencing episodic diversifying selection (0.05 significance) by mixed effects model evolution (MEME).
  3. cPositively selected sites detected using the Bayes empirical approach implemented in the site models M8 and M2a. Number of positively selected sites detected at the posterior probability ≥0.99 and 0.95 are indicated in parenthesis. ω computed using M8 and M2a are also presented.
  4. dNumber of sites evolving under the influence of pervasive diversifying selection, detected by FUBAR at 0.9 posterior probability.
  5. e Number of sites evolving under the influence of pervasive purifying selection, detected by FUBAR at 0.9 posterior probability.
  6. ω = mean dN/dS.
  7. NS = not significant at 0.05 compared to the null model (M7: beta).