Table 5 Significantly enriched GO (gene ontology) functional annotation of predicted target genes of differentially expressed miRNAs during E. coli or S. aureus challenge of MAC-T cells

Biological adhesion

Bta-miR-23a

58

0.038 (0.11)

-

-

-

Biological regulation

Bta-miR193a-3p

159

0.002 (0.039)

Bta-miR-24-3p

287

0.010 (0.070)

Bta-miR365-3p

142

5.5E-5 (3.9E-4)

Bta-miR-148a

356

1.7E-8 (1.3E-7)

Bta-miR-30b-5p/30c

642

4.4E-6 (3.2E-5)

Bta-miR-23a

565

4.0E-9 (4.2E-8)

Bta-miR-499

135

0.045 (0.11)

Bta-miR-92a

441

7.2E-10 (1.6E-8)

Bta-miR-99b

31

0.007 (0.060)

-

-

-

Cellular component organization

Bta-miR-30b-5p/30c

235

2.4E-4 (0.001)

Bta-miR-2339

46

0.002 (0.016)

Bta-let-7a-5p

182

0.040 (0.120)

Bta-miR-23a

192

0.004 (0.016)

Bta-miR-499

60

0.001(0.008)

Bta-miR-92a

144

0.016 (0.049)

Bta-miR-148a

127

9.4E-4 (0.005)

Bta-miR-184

22

0.006 (0.080)

Cellular process

Bta-miR193a-3p

207

0.009 (0.096)

Bta-miR-24-3p

411

1.1E-6 (2.3E-5)

Bta-miR423-5p

337

0.034 (0.160)

Bta-miR-148a

468

2.1E-9 (4.7E-8)

Bta-miR365-3p

180

5.7E-4 (0.003)

Bta-miR-2339

143

0.002 (0.020)

Bta-miR-30b-5p/30c

889

1.1E-10 (2.5E-9)

Bta-miR-23a

766

1.1E-13 (2.4E-12)

Bta-let-7a-5p

732

1.3E-5 (2.5E-4)

Bta-miR-486-5p

140

0.007 (0.067)

Bta-miR-499

198

8.2E-6 (1.6E-4)

Bta-miR-92a

567

2.0E-7 (1.4E-6)

Bta-miR-99b

37

0.036 (0.100)

-

-

-

Death

Bta-miR193a-3p

21

0.038 (0.190)

Bta-miR-24-3p

35

0.046 (0.220)

Bta-miR-30b-5p/30c

70

0.031 (0.083)

Bta-miR-21-3p

7

0.044 (0.930)

Bta-let-7a-5p

61

0.026 (0.087)

Bta-miR-92a

47

0.037 (0.084)

Bta-miR-499

21

0.014 (0.045)

-

-

-

Developmental process

Bta-miR193a-3p

71

0.028 (0.190)

Bta-miR-24-3p

151

1.0E-5 (1.0E-4)

Bta-miR423-5p

114

0.024 (0.150)

Bta-miR-148a

182

3.7E-9 (4.1E-8)

Bta-miR365-3p

80

5.8E-7 (1.3E-5)

Bta-miR-2339

57

7.1E-4 (0.015)

Bta-miR-30b-5p/30c

312

9.1E-8 (1.0E-6)

Bta-miR-23a

272

2.2E-8 (1.5E-7)

Bta-let-7a-5p

241

0.001 (0.008)

Bta-miR-486-5p

56

0.001 (0.022)

Bta-miR-499

74

4.1E-4 (0.004)

Bta-miR-92a

212

7.8E-8 (8.5E-7)

Bta-miR-99b

19

0.002 (0.030)

-

-

-

Establishment of localization

Bta-miR423-5p

110

3.4E-4 (0.007)

Bta-let-7a-5p

205

0.004 (0.011)

Bta-miR-30b-5p/30c

243

9.9E-4 (0.004)

Bta-miR-92a

159

0.003 (0.009)

Growth

Bta-miR-99b

4

0.016 (0.088)

Bta-miR-23a

20

0.026 (0.088)

Localization

Bta-miR423-5p

119

8.8E-4 (0.009)

Bta-miR-148a

147

0.001 (0.005)

Bta-miR-30b-5p/30c

280

7.0E-5 (3.9E-4)

Bta-miR-2339

49

0.015 (0.078)

Bta-let-7a-5p

233

7.2E-4 (0.008)

Bta-miR-92a

182

4.8E-4 (0.002)

Bta-miR-499

68

0.002 (0.008)

-

-

-

Locomotion

Bta-miR193a-3p

14

0.049 (0.200)

Bta-miR-92a

31

0.030 (0.080)

Bta-miR-499

17

0.002 (0.009)

-

-

-

Metabolic process

Bta-miR365-3p

139

9.6E-4 (0.004)

Bta-miR-148a

334

0.001 (0.006)

Bta-let-7a-5p

538

0.001 (0.008)

Bta-miR-23a

559

1.8E-6 (9.7E-6)

Bta-miR-99b

30

0.025 (0.081)

Bta-miR-92a

395

0.039 (0.084)

Multicellular organismal process

Bta-miR365-3p

94

2.3E-5 (2.4E-4)

Bta-miR-24-3p

167

0.050 (0.190)

Bta-miR-30b-5p/30c

372

0.001 (0.004)

Bta-miR-148a

196

0.005 (0.015)

Bta-miR-499

84

0.027 (0.077)

Bta-miR-92a

258

2.2E-5 (1.2-E4)

Bta-miR-99b

20

0.023 (0.095)

-

-

-