Table 4 Number of KEGG orthologs (KO) in pathways with top mapped KOs

ko00230, Purine metabolism

Metabolism/Nucleotide metabolism

67

ko03040, Spliceosome

Genetic information processing/Transcription

52

ko05200, Pathways in cancer

Human diseases/Cancers

49

ko03013, RNA transport

Genetic information processing/Translation

47

ko05166, HTLV-I infection

Human diseases/Infectious diseases: Viral

44

ko00240, Pyrimidine metabolism

Metabolism/Nucleotide Metabolism

42

ko04110, Cell cycle

Cellular processes/Cell growth and death

42

ko04510, Focal adhesion

Cellular processes/Cell communication

38

ko04910, Insulin signaling pathway

Organismal systems/Endocrine system

35

ko03008, Ribosome biogenesis in eukaryotes

Genetic information processing/Translation

35

ko05016, Huntington's disease

Human diseases/Neurodegenerative diseases

34

ko04146, Peroxisome

Cellular processes/Transport and catabolism

34

ko00561, Glycerolipid metabolism

Metabolism/Lipid metabolism

32

ko05010, Alzheimer's disease

Human diseases/Neurodegenerative diseases

32

ko04010, MAPK signaling pathway

Environmental information processing /Signal transduction

32

ko04111, Cell cycle - yeast

Cellular processes/Cell growth and death

32

ko04144, Endocytosis

Cellular processes/Transport and catabolism

31

ko04810, Regulation of actin cytoskeleton

Cellular processes/Cell motility

30

ko00564, Glycerophospholipid metabolism

Metabolism/Lipid metabolism

29

ko05169, Epstein-Barr virus infection

Human diseases/Infectious diseases: Viral

29

ko00260, Glycine, serine and threonine metabolism

Metabolism/Amino acid metabolism

28

ko04120, Ubiquitin mediated proteolysis

Genetic information processing/Folding, sorting and degradation

28

ko04113, Meiosis - yeast

Cellular processes/Cell growth and death

28

ko03010, Ribosome

Genetic information processing/Translation

25

ko04145, Phagosome

Cellular processes/Transport and catabolism

25