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Table 1 Enrichment of gene ontology terms in differentially expressed sequences in P. bursaria detected by PAGE

From: Comparison of gene expression of Paramecium bursaria with and without Chlorella variabilissymbionts

GO_name

GO_id

Number of sequences

Zscore

P-value

False discovery rate

BP oxidation–reduction process

GO:0055114

135

-6.992

2.71E-12

3.28E-10

MF oxidoreductase activity

GO:0016491

92

-6.879

6.04E-12

3.65E-10

BP metabolic process

GO:0008152

104

-5.659

1.52E-08

6.15E-07

BP carbohydrate metabolic process

GO:0005975

33

-4.656

3.23E-06

9.76E-05

CC integral to membrane

GO:0016021

196

-4.399

1.09E-05

0.0003

BP translation

GO:0006412

56

-4.187

2.83E-05

0.0006

MF structural constituent of ribosome

GO:0003735

57

-4.153

3.29E-05

0.0006

CC ribosome

GO:0005840

54

-4.044

5.25E-05

0.0008

MF pyridoxal phosphate binding

GO:0030170

13

-4.015

5.96E-05

0.0008

MF phosphorelay response regulator activity

GO:0000156

40

3.310

0.0009

0.0102

BP phosphorelay signal transduction system

GO:0000160

40

3.310

0.0009

0.0102

BP ATP hydrolysis coupled proton transport

GO:0015991

16

-3.239

0.0012

0.0121

MF chromatin binding

GO:0003682

21

3.107

0.0019

0.0176

BP DNA replication

GO:0006260

18

3.008

0.0026

0.0227

CC intracellular

GO:0005622

95

-2.953

0.0031

0.0254

MF phosphorelay sensor kinase activity

GO:0000155

26

2.901

0.0037

0.0281

BP biosynthetic process

GO:0009058

16

-2.798

0.0051

0.0366

  1. Notes: GO, gene ontology; PAGE, parametric analysis of gene set enrichment; BP, biological process; MF, molecular function; and CC, cellular component. We used log2 Fold Change values between symbiont-bearing and symbiont-free cells to calculate Z scores and corresponding P-values for each GO term.