Skip to main content

Table 1 Samples and known mutations

From: Target enrichment using parallel nanoliter quantitative PCR amplification

Samples   Mutations:    
Name Type Gene name Genomic location cDNA position Protein position
BT-549 Breast cancer cell line PTEN 10:89720672 c.823delG p.V275fs*1
CCRF-CEM Leukemia cancer cell ine CDKN2A 9:21968228 c.1_471del471  
    9:21971002 c.317_522del206  
   MLH1 3:37042536 c.298C > T p.R100*
    3:37056036 c.790 + 1G > A  
   NOTCH1 9:139399362 c.4783_4784ins36 p.R1595 > PRLPHNSSFHFLR
   PTEN 10:89653782 c.80_492del413  
HCT116 Colon cancer cell line CDKN2A 9:21974758 c.68_69insG p.R24fs*20
    9:21994234 c.220_220delG p.E74fs*15
   MLH1 3:37056000 c.755C > A p.S252*
IGROV-1 Ovarian cancer cell ine MLH1 3:37070378 c.1513delA p.S505fs*3
   MSH6 2:48030647 c.3261delC p.F1088fs*2
PC3 Prostate cancer cell line PTEN 10:89685270 c.165_1212del1048 p.R55fs*1
SN12C Kidney cancer cell line NF2 22:30032739 c.115-1G > C  
786-O Kidney cancer cell line CDKN2A 9:21974677 c.1_150del150  
    9:21984138-21984453 c.1_316del316  
   PTEN 10:89692961 c.445C > T p.Q149*
   VHL 3:10183842 c.311delG p.G104fs*55
ACHN Kidney cancer cell line CDKN2A 9:21968228 c.1_471del471  
    9:21971002 c.317_522del206  
   NF2 22:30032794 c.169C > T p.R57*
DU-145 Prostate cancer cell line CDKN2A 9:21971108 c.250G > T p.D84Y
   MLH1 3:37038108 c.117-2A > T  
HCT-15 Colon cancer cell line APC 5:112177787 c.6496C > T p.R2166*
    5:112175539 c.4248delC p.I1417fs*2
   BRCA2 13:32913837 c.5351delA p.N1784fs*7
    13:32913837 c.3599_3600delGT p.C1200fs*1
   MSH6 2:48032121 c.3511_3516 > T p.D1171fs*4
    2:48025990 c.868delC p.L290fs*1
HT-29 Colon cancer cell line APC 5:112173848 c.2557G > T p.E853*
    5:112175957 c.4666_4667insA p.T1556fs*3
MCF7 Breast cancer cell line CDKN2A 9:21971002 c.317_522del206  
    9:21968228 c.1_471del471  
MDA-MB-231 Breast cancer cell line CDKN2A 9:21967751 c.1_522del522  
    9:21968228 c.1_471del471  
   NF2 22:30057209 c.691G > T p.E231*
MOLT-4 Leukemia cancer cell line CDKN2A 9:21967751 c.1_522del522  
    9:21968228 c.1_471del471  
   NOTCH1 9:139390649 c.7544_7545delCT p.P2515fs*4
   PTEN 10:89717775. c.800delA p.K267fs*9
OVCAR-5 Ovarian cancer cell line CDKN2A 9:21967751 c.1_522del522  
    9:21968228 c.1_471del471  
Normal1 Healthy normal1 control DNA     
Normal2 Healthy normal2 control DNA     
  1. NCI60 cell lines and normal control DNA samples included in this study with a list of known mutations per cel line.
  2. In nonsense or frameshift mutations the *symbol indicates the loss of the amino acid coding potential of the DNA sequence.