Gene sets over-expressed in CT26 versus normal colon. A). The top 10 over-expressed gene sets. Gene sets included those curated from literature and overexpression was determined using GenePattern . B-F): gene set enrichment for the targets of specific genes, including the GenePattern enrichment plot showing the enrichment plot (green) and the location of the individual gene set members in the expression ranked-ordered list (black vertical lines). The plot on the right (blue bars) shows the expression of the targeting gene RB1 (B), E2H2 (C), LIN9 (D), FOXO3 (E) and E2F1 (F).