Correlation and networks for worm burden and IFN-γ phenotype genes. (A) Spearman rank correlation (in box) of worm burden with IFN-γ response phenotype. (B) Hypothetical gene network modulating worm burden based on gene correlations between genes in TM4 and TM5. Solid blue lines represent correlations between -0.7 and -0.5, broken blue lines between -1.0 and -0.7. Solid and broken red lines represent the equivalent positive correlations. Phenotypes are in white boxes, TM4 genes are in green boxes and TM5 genes are in red boxes. p ≤ 0.01 in all cases.