Figure 6

Trinucleotide bias vs gene density. Scatterplot of trinucleotide compositional bias (Correspondence analysis 1rst Principal Coordinate) at 40Kb vs. gene coverage (ie, proportion of nucleotides in a genomic fragment, being part of a gene) for all 40K genomic fragments, overlapped by 39K. TgTAS-like associated fragments are painted black. A strong non-linear relation can be appreciated between the variables, where low gene density regions (including gene-depleted regions) present a particular trinucleotide composition (high 1PC). Also, there is a negative linear component relating both variables (Pearson’s correlation coefficient –0.445, p-value < 10 ^-16).