Genome-wide copy number variant discovery in dogs using the CanineHD genotyping array

BMC Genomics

Table 3 The stringent list of 15 single breed CNVRs

CNVR no.	Chr	Start	End	Length	No. of genes	Type	Breed	No. of affected	No. of screened	Freq. in breed	Genes**
78*	21	40,580,407	40,742,936	162,529	1	del	Finnish Spitz	4	12	0.33	PDE3B
2	1	65,361,010	65,528,809	167,799	1	del	Elkhound	2	12	0.17	TRDN
16	3	93,757,480	94,035,855	278,375	2	dupl	English Bulldog	2	12	0.17	ANAPC13, LCORL
23	4	82,705,831	82,993,500	287,669	0	del	Weimaraner	8	26	0.31
37	8	28,122,926	28,265,491	142,565	0	del	Greenland Sledge	3	12	0.25
47	13	14,209,388	14,411,209	201,821	0	del	Brittany Spaniel	5	12	0.42
48	13	21,103,428	22,714,370	1,610,942	11	dupl	Standard Poodle	2	12	0.17	DSCC1, TNFRSF11B, ENPP2, COLEC10, NOV, TAF2, MRPL13, DEPTOR, COL14A1, MTBP, SNTB1
57	15	37,836,364	37,940,678	104,314	1	dupl	Shar Pei	2	11	0.18	NDUFA12
58	16	45,458,552	45,682,702	224,150	0	del	Border Collie	2	9	0.22
68	19	13,325,414	13,514,903	189,489	0	del	Eurasian	3	11	0.27
69	19	13,816,712	15,228,649	1,411,937	3	dupl	Shar Pei	2	11	0.18	C4ORF33, SCLT1, PHF17
71	19	29,002,373	30,541,395	1,539,022	1	dupl	Border Collie	3	9	0.33	CNTNAP5
82	22	21,232,747	21,306,657	73,910	0	dupl	Eurasian	3	11	0.27
96	32	37,679,695	37,939,968	260,273	0	del	Dalmatian	2	7	0.29
103	35	23,792,470	23,921,812	129,342	0	del	German Shepherd	3	11	0.27

*The single breed CNVR no. 78 was previously found by Berglund et al. in the same breed [31].
**Genes in bold are completely within the estimated CNVR boundaries, see also Additional file 1: Table S6.

ISSN: 1471-2164