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Table 3 Gene function and pathway analysis of 31 differentially expressed genes between the mammary gland of two cows with high milk protein and fat percentage and two cows with low protein and fat percentage with IPA

From: Transcriptional profiling of mammary gland in Holstein cows with extremely different milk protein and fat percentage using RNA sequencing

Pathway

Functional annotation

p-value

Gene

Lipid metabolism

Export of cholesterol

3.36e-04

SAA1

Lipid metabolism

Accumulation of beta-estradiol

6.73e-04

SAA1

Lipid metabolism

Concentration of bile acid

6.38e-03

ATF3

Apoptosis of epithelial cell lines

Cell death of connective tissue cells

Cell death of epithelial cells

development of endothelial cell lines

Lipid metabolism

Quantity of steroid

8.53e-03

ATF3, SAA1

Lipid metabolism

Fatty acid metabolism

1.25e-02

TRIB3, SAA1

Lipid metabolism

Efflux of cholesterol

2.27e-02

SAA1

Lipid metabolism

Homeostasis of cholesterol

2.37e-02

SAA1

Lipid metabolism

Metabolism of cholesterol

3.16e-02

SAA1