Molecular functions associated with the up- and downregulated genes. The x-axis shows the categories of molecular functions. The y-axis represents the number of genes associated with selected cellular functions. The genes that were upregulated are indicated by dark columns, whereas the genes that were downregulated are depicted by bright columns. The cut-off of gene-expression changes was 1.50. A. Data obtained 3 h after pMCAO for the ischemic rat cortex under Semax treatment; B. Data obtained 24 h after pMCAO for the ischemic rat cortex under Semax treatment.