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Table 2 Genes related to the immune system and exhibited Semax-induced alteration of expression levels

From: The peptide semax affects the expression of genes related to the immune and vascular systems in rat brain focal ischemia: genome-wide transcriptional analysis

  Genes related to the immune system (9 genes): Gene symbol ENTREZ GENE_ID Fold change P-value
3h MHC (major histocompatibility class) I and II:     
RT1 class I, CE15 (RT1-CE15), mRNA. RT1-CE15 414789 0.43 4.0E-06
RT1 class I, M6, gene 2 (RT1-M6-2), mRNA. RT1-M6-2 365527 0.64 3.0E-03
RT1 class II, locus Db1 (RT1-Db1), mRNA. RT1-Db1 294270 0.55 7.6E-04
RT1 class II, locus Ba, mRNA. RT1-Ba 309621 0.51 3.1E-07
CD74 antigen (invariant polpypeptide of MHC class II antigen-associated), mRNA. Cd74 25599 0.50 1.6E-09
RT1 class Ia, locus A1, mRNA. RT1-A1 24973 0.50 7.6E-10
histocompatibility 2, class II antigen E alpha, mRNA. H2-Ea 294269 0.49 4.1E-10
Others:     
Prostaglandin-endoperoxide synthase 2, mRNA. Ptgs2/Cox2 29527 2.00 8.3E-34
Intercellular adhesion molecule 1, mRNA. Icam1 25464 1.61 9.9E-05
24h Genes related to the immune system (36 genes):     
immunoglobulins:     
Similar to immunoglobulin heavy chain variable region, mRNA. LOC500734 500734 15.37 7.5E-11
Similar to immunoglobulin kappa-chain, mRNA. LOC500172 500172 11.57 2.1E-34
Similar to Immunoglobulin kappa-chain VJ precursor, mRNA. LOC500161 500161 8.31 2.1E-34
Similar to gamma-2a immunoglobulin heavy chain, mRNA. LOC362796 362796 8.20 2.1E-34
Similar to immunoglobulin heavy chain variable region, mRNA. LOC314492 314492 6.53 2.0E-06
Similar to immunoglobulin kappa-chain, mRNA. LOC500194 500194 6.27 2.1E-34
Similar to Immunoglobulin kappa-chain VJ precursor, mRNA. LOC502789 502789 6.00 3.7E-20
Similar to immunoglobulin kappa-chain, mRNA. LOC502843 502843 5.74 1.7E-19
Similar to immunoglobulin kappa-chain, mRNA. LOC502797 502797 5.48 5.5E-11
Similar to IG kappa-chain V-V region K2 precursor, mRNA. LOC500180 500180 4.67 4.8E-08
Similar to Igh-1a_predicted protein, mRNA. LOC503073 503073 3.67 7.3E-14
Similar to NGF-binding Ig light chain, mRNA. LOC502820 502820 3.60 5.6E-23
Similar to immunoglobulin heavy chain variable region, mRNA. LOC500733 500733 3.08 5.3E-14
Immunoglobulin heavy chain 1a (serum IgG2a), mRNA. Igh-1a 299352 2.97 3.5E-26
Similar to NGF-binding Ig light chain, mRNA. LOC500183 500183 2.91 3.8E-22
Similar to Immunoglobulin kappa-chain VJ precursor, mRNA. LOC500162 500162 2.80 1.7E-04
Similar to immunoglobulin heavy chain variable region, mRNA. LOC503070 503070 2.70 1.6E-03
Similar to Immunoglobulin kappa-chain VJ precursor, mRNA. LOC500163 500163 2.62 8.6E-03
Similar to immunoglobulin light chain variable region, mRNA. LOC363828 363828 2.52 9.7E-03
Similar to IG light chain Vk region Y13-259, mRNA. LOC500181 500181 1.85 3.2E-07
Similar to Ig kappa light chain precursor, mRNA. LOC500177 500177 1.76 3.2E-06
Similar to immunoglobulin light chain variable region, mRNA. LOC502831 502831 0.34 6.3E-06
Chemokines:     
Chemokine (C-X-C motif) ligand 13, mRNA. Cxcl13 498335 4.12 1.6E-08
Chemokine (C-X-C motif) ligand 9, mRNA. Cxcl9 246759 2.42 1.8E-14
Chemokine (C-X-C motif) ligand 10, mRNA. Cxcl10 245920 2.32 1.9E-03
Chemokine (C-C motif) ligand 5, mRNA. Ccl5 81780 1.98 6.5E-05
Chemokine (C-X-C motif) ligand 11, mRNA. Cxcl11 305236 1.85 2.1E-03
Chemokine (C-C motif) ligand 7, mRNA. Ccl7 287561 1.78 8.3E-04
Chemokine (C-C motif) ligand 19, mRNA. Ccl19 362506 1.72 3.4E-05
Chemokine (C-C motif) ligand 20, mRNA. Ccl20 29538 0.44 3.4E-05
MHC (major histocompatibility class) I and II:     
RT1 class II, locus Ba, mRNA. RT1-Ba 309621 2.28 1.5E-15
RT1 class I, A3, mRNA. RT1-A3 309627 1.96 4.6E-06
RT1 class Ia, locus A1, mRNA. RT1-A1 24973 1.94 2.8E-11
RT1 class I, T24, gene 4, mRNA. RT1-149 414784 1.86 3.8E-10
Histocompatibility 2, M region locus 10.6, mRNA. H2-M10.6 414787 1.77 2.0E-06
CD74 antigen (invariant polpypeptide of MHC class II antigen-associated), mRNA. Cd74 25599 1.63 5.3E-06
  1. Entrez Gene is NCBI's repository for gene-specific information. In the table, P-values are in the form of an exponential number format.