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Table 4 Genes related to the vascular system and exhibited Semax-induced alteration of expression levels

From: The peptide semax affects the expression of genes related to the immune and vascular systems in rat brain focal ischemia: genome-wide transcriptional analysis

  Genes related to the vascular system (24 genes): Gene symbol ENTREZ GENE_ID Fold change P-value
3h Cysteine-rich, angiogenic inducer, 61, mRNA. Cyr61 83476 2.43 1.5E-07
Activating transcription factor 3, mRNA. Atf3 25389 2.24 3.9E-03
Kruppel-like factor 4 (gut), mRNA. Klf4 114505 2.23 2.0E-03
A disintegrin-like and metallopeptidse (reprolysin type) with thrombospondin type 1 motif, 1, mRNA. Adamts1 79252 2.18 5.2E-11
FBJ murine osteosarcoma viral oncogene homolog, mRNA. Fos 314322 2.11 2.0E-04
Jun B proto-oncogene, mRNA. Junb 24517 2.07 1.8E-06
Nuclear factor, interleukin 3 regulated, mRNA. Nfil3 114519 2.03 5.4E-08
Prostaglandin-endoperoxide synthase 2, mRNA. Ptgs2/Cox2 29527 2.00 8.3E-34
Brain derived neurotrophic factor, mRNA. Bdnf 24225 1.88 2.0E-04
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 5, mRNA. Smarca5 307766 1.74 2.9E-09
Zinc finger protein 36, mRNA. Zfp36 79426 1.73 5.5E-03
Early growth response 2, mRNA. Egr2 114090 1.70 6.6E-03
Dual specificity phosphatase 1, mRNA. Dusp1 114856 1.67 3.0E-08
Heat shock 27 kDa protein 1, mRNA. Hspb1 24471 1.63 9.0E-03
Intercellular adhesion molecule 1, mRNA. Icam1 25464 1.61 9.9E-05
Secretogranin II (chromogranin C), mRNA. Scg2 24765 1.60 3.6E-04
Relaxin 1, mRNA. Rln1 25616 1.58 4.0E-03
Amyloid beta (A4) precursor protein, mRNA. App 54226 0.66 1.9E-03
Mitogen activated protein kinase 10, mRNA. Mapk10 25272 0.66 2.6E-03
Fibronectin 1, mRNA. Fn1 25661 0.63 5.1E-04
Catalase, mRNA. Cat 24248 0.51 2.9E-05
RT1 class II, locus Ba, mRNA. RT1-Ba 309621 0.51 3.1E-07
CD74 antigen (invariant polpypeptide of MHC class II antigen-associated), mRNA. Cd74 25599 0.50 1.6E-09
RT1 class Ia, locus A1, mRNA. RT1-A1 24973 0.50 7.6E-10
24h Genes related to the vascular system (12 genes):     
Chemokine (C-X-C motif) ligand 9, mRNA. Cxcl9 246759 2.42 1.8E-14
Chemokine (C-X-C motif) ligand 10, mRNA. Cxcl10 245920 2.32 1.9E-03
RT1 class II, locus Ba, mRNA. RT1-Ba 309621 2.28 1.5E-15
Chemokine (C-C motif) ligand 5, mRNA. Ccl5 81780 1.98 6.5E-05
RT1 class Ia, locus A1, mRNA. RT1-A1 24973 1.94 2.8E-11
Chemokine (C-C motif) ligand 7, mRNA. Ccl7 287561 1.78 8.3E-04
Nephroblastoma overexpressed gene, mRNA. Nov 81526 1.64 3.2E-06
CD74 antigen (invariant polpypeptide of MHC class II antigen-associated), mRNA. Cd74 25599 1.63 5.3E-06
Secreted phosphoprotein 1, mRNA. Spp1 25353 1.58 3.4E-06
Plasminogen activator, tissue, mRNA. Plat 25692 0.65 1.1E-07
Podoplanin, mRNA. Pdpn 54320 0.63 5.3E-10
A disintegrin-like and metallopeptidse (reprolysin type) with thrombospondin type 1 motif, 1, mRNA. Adamts1 79252 0.56 7.5E-09
  1. Entrez Gene is NCBI's repository for gene-specific information. In the table, P-values are in the form of an exponential number format.