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Table 3 Comparison of expression change for some TFs of interest in Nfib - and Nr3c1 -knockout lungs

From: An overlapping set of genes is regulated by both NFIB and the glucocorticoid receptor during lung maturation

 

Nfib-KO

Nr3c1-KO

Gene

FC

p-value

FC

p-value

Nfib

*2.75

<10-5

2.17

0.001

Nr3c1

1.23

0.172

*3.14

<0.001

Nfia

2.27

0.001

0.61

0.006

Snai2

1.72

<10-5

1.54

0.003

Meis2

1.57

0.023

2.03

0.012

Nr2f1

1.83

0.001

1.66

0.003

  1. For each knockout, the table shows the expression fold change and the associated uncorrected p-value (see Methods). The expression changes for Nfib and Nr3c1 transcripts in their respective KO (marked by an asterisk) occurs in the context of the transcripts lacking an essential exon and thus no functional protein is expressed.
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BMC Genomics

ISSN: 1471-2164

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