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Figure 6 | BMC Genomics

Figure 6

From: Transcriptome profiling of granulosa cells of bovine ovarian follicles during growth from small to large antral sizes

Figure 6

Two upstream regulators of interest, STAT4 (A) and XBP1 (B), which are predicted to be activated and one regulator, MGEA5 (C), predicted to be inhibited in large follicles based on known interactions with genes in our data set by IPA. Interactions between molecules are shown as explained in the legend, with focus molecule symbols highlighted in color, based on up (red) or down (green) regulation in large follicles and of increasing intensity with degree of fold change. The suggested action of the central gene is indicated as up-(red) or down-(blue) regulating with the degree of confidence increasing with color intensity. Arrowheads at the end of interactions indicate activation, whereas bars indicate inhibitory effects. The unbroken arrows and the dashed arrows represent direct and indirect interactions respectively, between the genes and the upstream regulators.

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