Table 3 Genes which are down regulated in large follicles with respect to small folliclesâ€
Gene symbol | Fold change | Gene symbol | Fold change | Gene symbol | Fold change |
|---|---|---|---|---|---|
Cell cycle | |||||
RPRM | 5.8 | Â | Â | Â | Â |
Cell morphology | |||||
JAKMIP1 | 20.8 | MYO10 | 6.8 | ACTA1 | 3.4 |
SEPT4 | 15.3 | MFAP2 | 4.6 | MYO1D | 3.0 |
Cytokines, hormones and receptors | |||||
KIT | 23.1 | IL33 | 3.6 | GPR77 | 3.2 |
ANGPT2 | 11.5 | PTPRN2 | 3.6 | ANGPTL2 | 3.1 |
RYR2 | 7.0 | SHISA2 | 3.5 | F2RL2 | 3.1 |
PDGFC | 4.6 | CMTM8 | 3.4 | SFRP4 | 3.0 |
FGFR2 | 3.7 | IL20RA | 3.4 | Â | Â |
Directional cell growth | |||||
FEZ1 | 3.8 | EPHA1 | 3.2 | Â | Â |
Extracellular matrix and synthesis | |||||
LAMC2 | 3.4 | COL1A1 | 3.0 | Â | Â |
Intercellular and cell to matrix adhesion | |||||
NEDD9 | 5.9 | CDH2 | 4.0 | NPNT | 3.2 |
Protein trafficking | |||||
SNX31 | 6.0 | ADCK3 | 3.4 | MZB1 | 3.1 |
CLU | 4.9 | Â | Â | Â | Â |
Proteolysis and inhibition | |||||
*PTI | 5.6 | LTF | 4.0 | EPHX1 | 3.4 |
MMP16 | 4.0 | PRSS35 | 3.7 | TRIM2 | 3.3 |
RNA processing | |||||
CPEB1 | 3.9 | Â | Â | Â | Â |
Transcription regulation | |||||
MYC | 16.4 | FOS | 4.0 | EMX2 | 3.1 |
HOPX | 13.8 | FHL2 | 3.3 | MSX1 | 3.1 |
TGIF1 | 6.1 | HES1 | 3.2 | Â | Â |
Transport | |||||
SVOPL | 8.6 | NUP210 | 4.7 | AQP1 | 3.2 |
NALCN | 6.0 | ABCC8 | 4.7 | FXYD6 | 3.2 |
AP3B2 | 5.5 | STARD10 | 3.4 | ZP3 | 3.2 |
Other enzymes | |||||
GATM | 11.1 | MAN1A1 | 4.2 | PTGS2 | 3.5 |
CA14 | 8.8 | ENPP1 | 4.1 | ABAT | 3.5 |
PAPSS2 | 7.8 | HMOX1 | 4.1 | PFKFB3 | 3.2 |
RASL11B | 6.8 | PHGDH | 3.7 | CYP2C19 | 3.1 |
GALNT13 | 5.3 | RENBP | 3.6 | AKR1C3 | 3.1 |
AKR1B1 | 4.5 | DDO | 3.6 | GYLTL1B | 3.0 |
Other signalling | |||||
MEST | 28.7 | GUCA1A | 5.1 | *RGS2 | 3.4 |
TNFAIP2 | 17.5 | HLA-A | 4.4 | APBB2 | 3.2 |
IHH | 16.6 | *CHRDL1 | 3.7 | BANK1 | 3.1 |
CARTPT | 14.0 | SASH1 | 3.5 | *TCRA | 3.0 |
Other | |||||
LRRC17 | 7.1 | TTN | 3.6 | MMD | 3.1 |
STAC3 | 3.9 | SEL1L3 | 3.6 | BTNL1 | 3.1 |
LRRC1 | 3.8 | CCDC3 | 3.2 | TMIGD2 | 3.0 |