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Table 4 Gene Ontology terms enriched in response to temperature changes (Fisher’s exact test with multiple testing correction of FDR < 0.05, Benjamini and Hochberg)

From: Characterization of the transcriptome and temperature-induced differential gene expression in QPX, the thraustochytrid parasite of hard clams

GO term ID Gene ontology term description GO type FDR p-value % in DE groupa % on arrayb Fold enrichc
Up-regulated at 27°C       
GO:0006548 Histidine catabolic process P 2.9E-02 2.8E-05 5.4 0.0 151
GO:0016829 Lyase activity F 2.5E-02 8.0E-06 19.6 3.7 5
Down-regulated at 27°C       
GO:0019915 Lipid storage P 1.8E-02 2.2E-05 3.7 0.0 104
GO:0005840 Ribosome C 2.9E-02 5.7E-05 11.1 2.0 6
GO:0003735 Structural constituent of ribosome F 1.8E-02 2.9E-05 11.1 1.8 6
Up-regulated at 23°C       
GO:0006081 Cellular aldehyde metabolic process P 2.5E-02 3.2E-05 3.5 0.1 49
GO:0003755 Peptidyl-prolyl cis-trans isomerase activity F 1.3E-02 9.7E-06 4.4 0.1 30
GO:0000502 proteasome complex C 1.3E-02 1.2E-05 5.3 0.3 16
Down-regulated at 10°C       
GO:0006548 Histidine catabolic process P 8.1E-03 1.0E-05 2.4 0.0 69
GO:0008233 Peptidase activity F 4.9E-02 1.7E-04 11.0 3.9 3
GO:0016829 Lyase activity F 4.9E-02 1.9E-04 10.4 3.6 3
GO:0006081 Cellular aldehyde metabolic process P 4.9E-02 1.4E-04 2.4 0.1 33
GO:0016616 Oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor F 2.7E-02 4.3E-05 6.1 1.1 6
  1. aPercent of sequences with that gene ontology term in the differentially expressed gene group.
  2. bPercent of sequences with that gene ontology term on the whole array.
  3. cFold enrichment: Fold increase of the GO term in the differentially expressed gene group.
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BMC Genomics

ISSN: 1471-2164

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