From: Transcriptional profile of Paracoccidioides spp. in response to itraconazole
Functional category | Gene product | Best hit/Paracoccidioides genome locus | e-value | Number of occurrences a | |
---|---|---|---|---|---|
1 h | 2 h | ||||
Metabolism/Energy | 3-deoxy-7-phosphoheptulonate synthase (DAHP) | PAAG_03237 | 9.2e-29 | +2 | |
Cysteine desulfurase (CYSD) | PAAG_05850 | 2.2e-58 | +22 | ||
Betaine aldehyde dehydrogenase (BADH) | PAAG_05392 | 2.1e-19 | +2 | ||
NADP-specific glutamate dehydrogenase (GDH) | PAAG_07689 | 1.6e-26 | +1 | ||
NAD dependent epimerase dehydratase (EDH) | PAAG_05580 | 1.6e-30 | +1 | ||
Succinyl 3-ketoacid-coenzime A transferase (SCOT) | PAAG_05093 | 2.6e-17 | +1 | ||
Ribulose-phosphate 3-epimerase (RP3E) | PAAG_01632 | 6.5e-42 | -17 | ||
Aconitase (ACO) | PAAG_05328 | 5.8e-18 | -2 | ||
D-amino-acid oxidase (DAAO) | PAAG_02361 | 2.4e-38 | -3 | ||
Er-associated proteolytic system protein (ERAD) | PAAG_04633 | 8.6e-40 | -4 | ||
Isovaleryl-CoA dehydrogenase (IVD) | PAAG_06830 | 1.0e-23 | +4 | ||
Acyl-CoA dehydrogenase (ADH) | PAAG_05211 | 1.0e-30 | +1 | ||
Acyl-CoA dehydrogenase (ADH) | PAAG_01222 | 2.1e-19 | -8 | ||
Hormone-sensitive lipase (LIPE) | PAAG_06218 | 7.6e-37 | +1 | ||
Pyruvate kinase (PK) | PAAG_06380 | 3.1e-31 | +1 | ||
Aldehyde dehydrogenase (ALDH) | PAAG_05249 | 1.0e-44 | -4 | ||
Glutamine amidotranferase subunit pdxT (GLAT) | PAAG_07505 | 1.3e-23 | -5 | ||
ATP synthase f0 subunit 9 (ATPS9) | PAAG_12009 | 3.0e-17 | +22 | ||
Short chain dehydrogenase (DHS-14) | PAAG_04787 | 3.2e-48 | +1 | ||
Transcription | Transcription factor (STEA) | PAAG_00406 | 8.4e-50 | +3 | |
Isoform cra_b | PAAG_05467 | 3.2e-15 | +1 | ||
Fator transcrição tipo CCCH | PAAG_02735 | 4.2e-27 | +1 | ||
Pirin (PIR) | PAAG_04726 | 2.5e-52 | +7 | +47 | |
RING finger protein (RNF) | PAAG_06129 | 1.5e-18 | +2 | ||
Apses transcription (APSES) | PAAG_02379 | 1.6e-30 | +1 | ||
mRNA-nucleus export ATPase | PAAG_04548 | 4.0e-45 | -27 | ||
C6 transcription factor (CTFIB) | PAAG_01359 | 4.5e-65 | -12 | ||
Cell rescue, Defense and Virulence | |||||
Survival factor1 (SVF1) | PAAG_02425 | 4.7e-36 | +1 | ||
Gluthatione S-transferase (GST) | PAAG_03931 | 1.0e-33 | +1 | ||
Vanadate resistence protein | PAAG_03940 | 9.4e-54 | +2 | ||
Heat shock protein (STI1) | PAAG_06811 | 2.2e-24 | +2 | ||
Heat shock protein (HSP10) | PAAG_05142 | 6.5e-32 | +1 | +2 | |
Heat shock protein (HSP30) | PAAG_00871 | 5.4e-52 | -26 | -33 | |
Heat shock protein (HSP70) | PAAG_08003 | 4.4e-40 | +3 | ||
Heat shock protein (HSP60) | PAAG_08059 | 4.3e-55 | -12 | ||
Protein synthesis and biogenesis | |||||
ATP-dependent RNA helicase (ELF4A) | PAAG_00689 | 1.3e-24 | +7 | ||
Serine threonine-protein kinase (SRK1) | PAAG_06726 | 7.6e-66 | -2 | ||
40S ribosomal protein S4 (RPS4) | PAAG_03816 | 7.3e-37 | +2 | ||
Protein fate (folding, modification, destination) | |||||
Ubiquitin-protein ligase (UBI) | PAAG_02632 | 3.7e-11 | +2 | ||
WD repeat containing protein (WDR) | PAAG_00103 | 1.0e-25 | +1 | ||
Ubiquitin thioesterase (OTU1) | PAAG_08841 | 1.0e-32 | -5 | ||
Ubiquitin fusion degradation protein (UFD) | PAAG_01475 | 1.0e-62 | +1 | ||
Proteasome component (PREP6) | PAAG_07802 | 6.1e-5 | +1 | ||
Cellular transport, transport facilities and transport routes | |||||
Tetracycline resistance protein (TETA) | PAAG_01353 | 1.0e-56 | +13 | ||
Mfs transporter (MFS) | PAAG_02191 | 7.3e-56 | +9 | ||
Nucleoporin (SONB) | PAAG_02655 | 1.1e-36 | +1 | ||
Voltage-gated Ca2+ alpha subunit (CAV) | PAAG_01353 | 9.9e-15 | +1 | ||
Sodium-dependent phosphate transporter (SPIT) | PAAG_03892 | 1.5e-11 | +1 | ||
Zinc finger membrane protein (DHHC) | PAAG_06616 | 6.6e-53 | -4 | ||
autophagy regulatory protein | PAAG_04970 | 2.6e-33 | -2 | ||
GPR1/FUN34/YAAH family protein | PAAG_08587 | 1.2e-47 | -13 | -5 | |
Carnitine/acyl carnitine carrier (CAR) | PAAG_03452 | 1.7e-30 | -18 | -89 | |
General secretion pathway protein. | PAAG_05009 | 2.7e-60 | -10 | ||
Family integral membrane protein (IMP) | PAAG_03183 | 4.1e-50 | +1 | ||
Hemolisyn-iii channel protein (HLYiii) | PAAG_01871 | 6.0e-34 | +3 | ||
Integral membrane MPV17/PMP22 | PAAG_02868 | 6.6e-37 | -2 | ||
Vesicular fusion protein (SEC17) | PAAG_06233 | 2.8e-77 | -1 | ||
Biogenesis of Cellular Components (cell wall/membrane) | |||||
Chitin synthase regulator 2 (CHSr) | PAAG_04860 | 2.0e-17 | +3 | ||
Oxysterol-binding protein (OSBP) | PAAG_06807 | 3.6e-45 | +6 | ||
Diacylglycerol o-acyltransferase (DGAT) | PAAG_07527 | 1.4e-64 | +1 | ||
Phosphatidyl synthase (PHS) | PAAG_03571 | 6.5e-34 | +1 | ||
Cellular communication/Signal transduction mechanism | |||||
FluG Domain-containing protein | PAAG_05486 | 1.0e-53 | +1 | ||
Leucine –rich repeat Igi member 4 (LGI4) | PAAG_00833 | 1.0e-25 | +1 | ||
Conserved Lysine protein (LYS) | PAAG_03092 | 6.2e-43 | +2 | ||
Unclassified protein | Conserved hypothetical protein | PAAG_02735 | 1.3e-39 | +2 | |
Conserved hypothetical protein | PAAG_01353 | 1.3e-18 | +6 | ||
Conserved hypothetical protein | PAAG_07364 | 5.8e-30 | +4 | ||
Conserved hypothetical protein | PAAG_00520 | 3.9e-27 | +3 | ||
Conserved hypothetical protein | PAAG_02379 | 1.5e-19 | +2 | ||
Conserved hypothetical protein | PAAG_02210 | 1.8e-37 | +6 | ||
Conserved hypothetical protein | PAAG_02236 | 1.0e-15 | +1 | ||
Conserved hypothetical protein | PAAG_03559 | 4.8e-47 | +1 | ||
Conserved hypothetical protein | PAAG_03596 | 4.4e-83 | +3 | ||
Conserved hypothetical protein | PAAG_08759 | 1.5e-63 | +2 | ||
Conserved hypothetical protein | PAAG_07907 | 1.0e-42 | +2 | ||
Conserved hypothetical protein | PAAG_04000 | 1.0e-44 | -4 | ||
Conserved hypothetical protein | PAAG_06816 | 1.7e-8 | -2 | ||
Conserved hypothetical protein | PABG_06807 | 1.0e-51 | -6 | ||
Conserved hypothetical protein | PAAG_01871 | 1.0e-51 | -2 | ||
Conserved hypothetical protein | PAAG_07034 | 3.4e-33 | +2 | ||
Conserved hypothetical protein | PADG_04444 | 6.7e-17 | +2 | ||
Hypothetical protein | PAAG_02259 | 1.0e-18 | -3 | ||
Hypothetical protein | PAAG_02991 | 4.9e-37 | +1 | ||
Domain-containing protein (DUF1688) | PAAG_04000 | 7.5e-17 | +2 |