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Figure 4 | BMC Genomics

Figure 4

From: Integrative analyses of genetic variation, epigenetic regulation, and the transcriptome to elucidate the biology of platinum sensitivity

Figure 4

Findings from pyramid analysis. A) ABCD2 expression vs. carboplatin and cisplatin DSPs p = 0.019 (carboplatin) and p = 0.030 (cisplatin). B) miR-30d expression vs. carboplatin and cisplatin drug specific phenotypes (DSPs) p = 0.004 (carboplatin) and p = 0.020 (cisplatin). C) miR-30d expression vs. ABCD2 expression p = 8.57 × 10-5. D) rs11138019 genotype vs. ABCD2 expression p = 3.00 × 10-5. E) rs11138019 genotype vs. miR-30d expression p = 0.044. F) rs11138019 genotype vs. carboplatin and cisplatin DSPs p = 3.28 × 10-5 (carboplatin) and p = 2.60 × 10-5 (cisplatin).

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BMC Genomics

ISSN: 1471-2164

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