Figure 4

Multiple sequence alignment of sodium channel toxins and related precursors of M. gibbosus . Depressant insect β-NaTx-like (panel A) and α-NaTx-like precursors (B). Signal peptides are shown in grey; sequences in bold and capital letters correspond to mature sequences; identical residues of mature sequence are highlighted in yellow colour and the conserved Cysteines residues are highlight in red; post-translational modification at the C-terminal is illustrated in lower case. Precursor organization is shown by cartoon of the gene (top of the figure): signal peptide is shown in grey line; pro-peptide and mature peptide is shown in black line. Identity (% I) and E-values are shown on the right. Identity and E-values correspond to the precursor sequences.