Figure 3
From: Perinatal bisphenol A exposure promotes dose-dependent alterations of the mouse methylome
Regions of Altered Methylation (RAMs) in gene promoters. RAMs within ±1.5 kb flanking transcription start sites (TSSs) are represented. Each column separated by gray lines represents a single sample (4 per group), and each row represents a unique gene promoter region, ±1.5 kb from the TSSs (magenta dotted line). The known BPA-interacting genes queried from the Comparative Toxicogenomic Database are also indicated on the right. Two arrows pointing to the Myh7b and Slc22a12 gene promoters (in blue text) show candidate RAMs validated in a larger subset of animals.