Figure 4
From: Perinatal bisphenol A exposure promotes dose-dependent alterations of the mouse methylome
Enriched biological processes among genes harboring differential methylation. The genes harboring differential methylation within their promoters (FDR adjusted p-value & 0.05) were subjected to GO term enrichment analysis. (A) A total of 198 genes from Ctr vs. MG comparison, (B) 76 genes from Ctr vs. UG comparison, and (C) 371 genes from UG vs. MG comparison are used for the analysis, and enriched pathways are involved in basic biological processes, including basic cellular, metabolic, and immune and stimulus responses, as well as some binding activities. The enriched biological processes are graphed using REViGO software. The colors of the circles represent the various levels of statistical significance, where the darker shade represents more significance in p-values than the lighter one. The various sizes of the circles represent the number of genes in given GO terms. A complete list of GO terms including cellular components and molecular functions is available in Additional file 2: Table S4.