Visual gene-network analysis reveals the cancer gene co-expression in human endometrial cancer

BMC Genomics

Table 1 Module significance in ECs and GO analysis

Module	Correlation^awith phenotypic characteristics of ECs (p-value)			Gene ontology enrichment analysis
	Grade	Type	Stage	Term	p-value^b	FDR
Blue	−0.002 (9.0E⁻¹)	0.08 (2.2E⁻¹)	0.42 (6.0E⁻¹⁹)	Antigen processing	8.7E⁻¹²	1.7E⁻¹²
				TCA cycle	4.5E⁻¹²	2.1E⁻¹²
Green	0.006 (9.1E⁻¹)	−0.02 (6.1E⁻⁵)	0.01 (9.3E⁻¹)	Immune response	3.7E⁻⁴³	6.3E⁻⁴⁰
Turquoise	−0.17 (6.4E⁻³)	−0.19 (2.4E⁻³)	0.17 (6.2E⁻³)	Cell adhesion	2.9E⁻²⁹	1.1E⁻²⁹
Yellow	0.44 (1.2E⁻¹⁶)	0.34 (6.3E⁻⁹)	0.31 (2.1E⁻⁷)	Cell-cycle regulation	4.9E⁻³⁵	8.6E⁻³²

^aThe correlation coefficient was calculated from the module eigengenes (i.e., first principal component of the expression values across subjects) and phenotypic characteristics of ECs using Pearson correlation.
^bp-value used the Bonferroni-adjusted p-value.

ISSN: 1471-2164