Microsomic animals recover faster from a glucose challenge and show a lower systolic blood pressure (SBP) than control animals. Glucose tolerance test performed in M and C male mice fed with a normal (A) or a high-fat diet (hfd) for 18 weeks (C). Area under the curve (AUC) for the glucose tolerance test performed in M and C mice fed with normal (B) or high-fat diet (hfd) for 18 weeks (D) (*P < 0.05. Error bars, s.e.m.). SBP recorded in M and C males (E) and females (F) fed with a normal or hfd for 18 weeks, respectively. [a, b] indicate a significant difference at P < 0.05. Error bars, s.e.m. Survival rate in M and C male (G) and female (H) fed with or without hfd, respectively.