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Figure 8 | BMC Genomics

Figure 8

From: A comparison of performance of plant miRNA target prediction tools and the characterization of features for genome-wide target prediction

Figure 8

Characterization of features of true positive (TP) and false negative (FN) predictions in Arabidopsis and non-Arabidopsis datasets. (A) Distribution of first stretch of miRNA-mRNA targets in TPs and FNs for Arabidopsis and non-Arabidopsis datasets: i) and ii) show the length distribution for the TP and FN miRNAs in Arabidopsis dataset, respectively, while iii) and iv) show the length distributions for TP and FN datasets in non-Arabidopsis dataset, respectively. (B) Comparison of the ‘seed region’ (miRNA region with maximum continuous matches with its targets) in TPs and FNs for Arabidopsis and non-Arabidopsis dataset: i) and ii) are the lengths of seed region distributions for the TP and FN miRNAs in Arabidopsis species, respectively, while iii) and iv) represent the lengths of seed region distributions for TP and FN datasets in non-Arabidopsis datasets respectively. (C) Distribution of the match-mismatch ratio (number of matches divided by the number of mismatches for miRNA with its target sequences) in TPs and FNs for Arabidopsis and non-Arabidopsis datasets. i) and ii) show the match-mismatch ratio for the TP and FN miRNAs in Arabidopsis dataset respectively, while iii) and iv) are match-mismatch ratios of seed region distributions for TP and FN datasets in non-Arabidopsis dataset respectively. (D) Change in entropy with respect to the position of the miRNA:mRNA interaction. Entropy value for each miRNA-mRNA positions for TP predictions in Arabidopsis and non-Arabidopsis datasets and FN predictions for non-Arabidopsis datasets are plotted in black, red and blue respectively.

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