Figure 2

Annotated glycosyltransferases. Results for the model system Campylobacter jejuni are shown on the left panel and for L. rhamnosus GG on the right panel. Putative GTs were predicted using an HMM based screening. A: results obtained with an HMM recognizing ‘Rossmann-fold domains’, expected to be the HMM with the lowest specificity towards GTs (Table 1, class I). B and C: results obtained with a family of HMMs of intermediate specificity for GTs (Table 1, class II). D: results obtained with the class of HMMs, most specific for GTs (Table 1, class III). Pie charts indicate the extent to which different functional classes were enriched amongst the predictions obtained with the respective classes of HMMs. Slices indicated in red on the pie chart correspond to the functional classes of the predictions that were retained after the fold recognition filtering step. For each group of HMMs, the total number of predictions is denoted in black on top of every pie chart and the number of predictions retained after applying the fold recognition step is denoted in red.